Expanding neurodegeneration modelling
نویسندگان
چکیده
منابع مشابه
Mayhem of the multiple mechanisms: modelling neurodegeneration in prion disease.
This review examines recent attempts to advance the understanding of the mechanism by which neurones die in prion disease. Prion diseases or transmissible spongiform encephalopathies are characterized by the conversion of a normal glycoprotein, the prion protein, to a protease-resistant form that is suggested to be both the infectious agent and the cause of the rapid neurodegeneration in the di...
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ژورنال
عنوان ژورنال: Nature Reviews Neuroscience
سال: 2015
ISSN: 1471-003X,1471-0048
DOI: 10.1038/nrn3982